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Table 2 Comparison of T-score changes before and after MRONJ treatment in TPTD and non-TPTD groups

From: Treatment period and changes in bone markers according to the application of teriparatide in treating medication-related osteonecrosis of the jaw

 

TPTD group (n = 35)

 

Non-TPTD group (n = 41)

 

T-score

(mean ± SD)

Initial

MRONJ resolution

p-value

Initial

MRONJ resolution

p-value

Lumbar

-2.47 ± 0.91

-1.76 ± 0.89

0.004*

-2.30 ± 1.17

-2.04 ± 1.23

0.365

Femur neck

-2.47 ± 0.82

-2.25 ± 0.75

0.035*

-2.29 ± 0.68

-2.27 ± 0.72

0.733

Hip

-1.43 ± 0.99

-1.34 ± 0.64

0.378

-1.22 ± 0.69

-1.29 ± 0.68

0.465

  1. *p < 0.05 (Paired T-test); MRONJ, medication-related osteonecrosis of the jaw
  2. There was no significant difference in T-scores before MRONJ treatment between the TPTD and non-TPTD groups (lumbar, femur neck, hip T-scores; p = 0.552, 0.341, and 0.725, respectively)